Epitope Binning
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Epitope binning experiments go beyond basic binding assays to map the interaction regions (epitopes) where binders engage their targets. This allows researchers to differentiate between binders that target overlapping epitopes and those that bind distinct regions. By understanding the binding diversity, you can strategically select complementary candidates for therapeutic or diagnostic development.
Key Features:
Starts at 39$/interaction
Epitope Mapping: Identifies overlapping and distinct binding sites on the target.
Competition Studies: Reveals how binders interact in the presence of other candidates.
Lead Selection: Enables rational selection of complementary binders to ensure epitope diversity.
When to Use:
To differentiate among multiple binders targeting the same antigen.
For antibody discovery projects where diverse binding profiles are required.
To understand potential competition among binders for the same epitope.
Binders are systematically tested against the target protein and compared to other candidates in a competitive binding assay. This process identifies overlapping epitopes by observing how the binding of one candidate affects the ability of another to bind.
