Binding Screening
Last updated
Last updated
Protein binding screening is designed to quickly and efficiently evaluate large libraries of protein variants for their ability to bind a target of interest. This high-throughput workflow enables you to classify candidates as binders or non-binders while also categorizing their binding strength (e.g., weak, medium, or strong). By focusing on rapid and cost-effective assays, our screening service is ideal for early-stage discovery projects where prioritizing candidates is key.
Key Features:
Starts at 99$/protein. 21 days turnaround time.
Yes/No Binding Classification: Rapidly determine whether each variant binds to the target.
Binding Strength Categorization: Classifies binders as weak, medium, or strong (no KD values).
High Throughput: Capable of screening thousands of variants in a single campaign.
Cost-Effective: Optimized for large-scale projects without compromising data quality.
When to Use:
To triage large libraries of protein variants during early discovery phases.
To identify promising binders for subsequent detailed characterization.
When rapid and broad insights into binding potential are required.
If you need precise binding kinetics with KD values, see Affinity Characterization.
During a binding screen, protein variants are immobilized or presented in solution, and the target analyte is flowed over the experimental setup. Real-time binding events are monitored using bio-layer interferometry (BLI), and results are analyzed to classify each variant. Single-concentration measurements provide approximate binding strength, allowing you to prioritize strong binders while excluding non-binders or weak candidates
