Affinity Characterization

Our Protein Affinity Characterization workflow enables users to accurately characterize protein interactions and their binding kinetics to one or several protein targets of interest. The assay is designed to aid users to precisely rank and measure affinity differences across the panel of sequences. The workflow includes a high-quality multi-cycle kinetics assay across a large range of antigen concentrations, allowing the detection of better and more subtle differences in binding affinities.

You will be able to access the following information for each interaction pair:

• Protein Expression and Yield

• Dissociation Constant (KD)

• Kinetic Parameters (Kon and Koff)

After the workflow is completed, you will be able to explore the data directly in our foundry portal, compare results across experiments and select variants to be characterized on our other available workflows.