Adaptyv Bio - Docs
  • Getting started
  • Experiment Types
    • Binding Screening
    • Affinity Characterization
    • Epitope Binning
    • Thermostability
    • Custom Assay Development
  • Molecular and Target Scope
    • Supported Protein Formats
    • Target Characteristics
  • Project Workflow
    • 1. Experiment Configuration
    • 2. Build Phase
    • 3. Data Generation (Protein Testing)
    • 4. Analysis, Validation, and Reporting
  • Project Scale and Timelines
    • Pilot Projects
    • Project Scaling
    • Timelines and Communication
  • Technology
    • Biolayer Interferometry
  • Foundry FAQs
    • Binding Assays
  • Foundry Portal
    • Creating Experiments
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  1. Experiment Types

Thermostability

Thermostability testing enables researchers to assess the thermal stability of protein variants, a critical parameter for therapeutic and industrial applications. By measuring the melting temperature (T_m) and stability under various conditions, this assay complements binding studies to provide a comprehensive view of protein performance.

Key Features:

  • Melting Temperature (T_m): Determines the temperature at which the protein unfolds.

  • Buffer Optimization: Evaluates stability under various pH and ionic conditions.

  • Combined Analysis: Integrates thermostability data with binding profiles for a holistic view.

Last updated 4 months ago

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