This high-throughput workflow enables you to classify candidates as binders or non-binders while also categorizing their binding strength (e.g., weak, medium, or strong). By focusing on rapid and cost-effective assays, our screening service is ideal for early-stage discovery projects where prioritizing candidates is key.

Key Features:

  • Starts at 99$/protein. 21 days turnaround time.

  • Yes/No Binding Classification: Rapidly determine whether each variant binds to the target.

  • Binding Strength Categorization: Classifies binders as weak, medium, or strong (no KD values).

  • High Throughput: Capable of screening thousands of variants in a single campaign.

  • Cost-Effective: Optimized for large-scale projects without compromising data quality.

When to Use:

  • To triage large libraries of protein variants during early discovery phases.

  • To identify promising binders for subsequent detailed characterization.

  • When rapid and broad insights into binding potential are required.

  • If you need precise binding kinetics with KD values, see Affinity Characterization.

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How It Works

During a binding screen, protein variants are immobilized or presented in solution, and the target analyte is flowed over the experimental setup. Real-time binding events are monitored using bio-layer interferometry (BLI), and results are analyzed to classify each variant. Single-concentration measurements provide approximate binding strength, allowing you to prioritize strong binders while excluding non-binders or weak candidates