> ## Documentation Index
> Fetch the complete documentation index at: https://docs.adaptyvbio.com/llms.txt
> Use this file to discover all available pages before exploring further.

# ipTM

> Interface predicted TM-score from AlphaFold‑Multimer for complex/interface quality

ipTM is an AlphaFold‑Multimer metric estimating interface quality in protein complexes. Higher scores generally indicate better‑packed and more reliable interfaces.

* **Type**: Structure metric (AlphaFold‑Multimer interface confidence)
* **Goal**: Rank complexes by interface quality/confidence
* **Input**: Paired protein sequences and AlphaFold‑Multimer predictions

Resources: [alphafold](https://github.com/deepmind/alphafold)