# Adaptyv Bio Docs

## Docs

- [Foundry API](https://docs.adaptyvbio.com/api-reference/api-introduction.md): Submit protein sequences for experimental characterization and retrieve results programmatically.
- [Accept an experiment's quote and create an invoice](https://docs.adaptyvbio.com/api-reference/experiments/accept-an-experiments-quote-and-create-an-invoice.md): Convenience endpoint that does the same thing as `POST /quotes/{id}/confirm` but addressed by experiment ID — the server resolves the quote ID internally. Accepts the Stripe quote, creates a draft invoice, and transitions the experiment to WaitingForMaterials.
- [Create experiment](https://docs.adaptyvbio.com/api-reference/experiments/create-experiment.md): Creates a new experiment request for the Adaptyv Foundry platform.
- [Estimate experiment cost](https://docs.adaptyvbio.com/api-reference/experiments/estimate-experiment-cost.md): Calculates the estimated cost for an experiment without creating it. Useful for previewing costs before submission.
- [Get experiment](https://docs.adaptyvbio.com/api-reference/experiments/get-experiment.md): Returns full metadata for an experiment: workflow status, target and sequence details, assay parameters, and billing references.
- [Get experiment invoice](https://docs.adaptyvbio.com/api-reference/experiments/get-experiment-invoice.md): Returns invoice metadata for a confirmed experiment, including the hosted payment URL. Available once `stripe_invoice_url` appears in the experiment detail; timing depends on organization billing settings.
- [Get experiment quote](https://docs.adaptyvbio.com/api-reference/experiments/get-experiment-quote.md): Returns quote metadata: totals, currency, status, and expiration. Available once `stripe_quote_id` appears in the experiment detail. The `expires_at` field shows when the quote expires if not confirmed.
- [Get experiment quote PDF](https://docs.adaptyvbio.com/api-reference/experiments/get-experiment-quote-pdf.md): Returns the quote as a PDF containing itemized pricing, terms, and experiment configuration. Response content-type is `application/pdf`.
- [List experiment updates](https://docs.adaptyvbio.com/api-reference/experiments/list-experiment-updates.md): Returns updates for one experiment, oldest first (chronological). Update types include `status_change`, `progress`, and `error`. Filter by type using `filter=eq(type,status_change)`.
- [List experiments](https://docs.adaptyvbio.com/api-reference/experiments/list-experiments.md): Lists experiments accessible to the caller, sorted by creation date (newest first). Experiments progress from submission through review, production, and analysis until results are available.
- [List results for an experiment](https://docs.adaptyvbio.com/api-reference/experiments/list-results-for-an-experiment.md): Returns all analysis results associated with a specific experiment. Results appear when the experiment's `results_status` field reaches `Partial` or `All`. Supports pagination via `limit` and `offset` query parameters.
- [List sequences for an experiment](https://docs.adaptyvbio.com/api-reference/experiments/list-sequences-for-an-experiment.md): Returns all sequences associated with a specific experiment. Results are sorted by creation date (newest first) and can be searched by name or amino acid content. Supports pagination via `limit` and `offset` query parameters.
- [Submit experiment](https://docs.adaptyvbio.com/api-reference/experiments/submit-experiment.md): Submits a draft experiment for review. Advances from Draft to WaitingForConfirmation by finalizing the Stripe quote. To accept an already-submitted quote, use `POST /experiments/{id}/quote/confirm`.
- [Update experiment](https://docs.adaptyvbio.com/api-reference/experiments/update-experiment.md): Modify an existing experiment's configuration or status.
- [Submit feedback, bug reports, or feature requests](https://docs.adaptyvbio.com/api-reference/feedback/submit-feedback-bug-reports-or-feature-requests.md): Use this endpoint to give us feedback, report bugs that are not already caught by our observability, or request features (or have your agents do it).
- [Accept quote](https://docs.adaptyvbio.com/api-reference/quotes/accept-quote.md): Finalizes and accepts a Stripe quote, creating a draft invoice. The linked experiment advances to `WaitingForMaterials`. Optionally attach a purchase order number for your records.
- [Get quote](https://docs.adaptyvbio.com/api-reference/quotes/get-quote.md): Returns the full quote document with itemized pricing, totals, expiration, and status, combined with experiment metadata (org name, notes).
- [List quotes](https://docs.adaptyvbio.com/api-reference/quotes/list-quotes.md): Returns every quote recorded for the caller's organization. Use this list to monitor pending proposals, track which quotes have already been accepted or expired, and review pricing history before moving to the detail or acceptance endpoints.
- [Reject quote](https://docs.adaptyvbio.com/api-reference/quotes/reject-quote.md): Cancels the quote on Stripe and records the rejection reason and optional feedback in the database. The linked experiment reverts to `Draft` so it can be modified and re-submitted.
- [Get result](https://docs.adaptyvbio.com/api-reference/results/get-result.md): Returns detailed result data including the full `summary` array with kinetic parameters (kon, koff, KD), binding curves, and quality metrics. The `data_package_url` field contains the data package URL, same as in the Foundry portal.
- [List results](https://docs.adaptyvbio.com/api-reference/results/list-results.md): Lists completed analysis results, sorted by creation date (newest first). Results appear when an experiment's `results_status` field reaches `Partial` or `All`. Paginate with `limit` (default 50) and `offset`; the response includes `total` for page calculation.
- [Add sequences to experiment](https://docs.adaptyvbio.com/api-reference/sequences/add-sequences-to-experiment.md): Appends sequences to a draft experiment identified by its human-readable code (e.g., "PROJ-001"). The experiment must be in Draft status; confirmed or later-stage experiments cannot accept new sequences. Create a new experiment to submit additional sequences if the original has progressed past draft…
- [Get sequence](https://docs.adaptyvbio.com/api-reference/sequences/get-sequence.md): Returns full details for a specific sequence including the complete amino acid string, metadata, and a reference to the containing experiment.
- [List sequences](https://docs.adaptyvbio.com/api-reference/sequences/list-sequences.md): Returns sequences from all experiments the caller has access to. Results are sorted by creation date (newest first). Filter by `experiment_id` to retrieve sequences for a specific experiment, or use `search` to match against sequence names or amino acid content.
- [Get custom target request](https://docs.adaptyvbio.com/api-reference/targets/get-custom-target-request.md): Retrieves full details of a custom target request, including sequence data, PDB information, and metadata. Returns 404 if the request doesn't exist or belongs to a different organization.
- [Get target](https://docs.adaptyvbio.com/api-reference/targets/get-target.md): Returns the catalog record for a single target by UUID.
- [List custom target requests](https://docs.adaptyvbio.com/api-reference/targets/list-custom-target-requests.md): Returns custom target requests for your organization, sorted by creation date (newest first). Supports filtering by status using the `filter` parameter (e.g. `filter=eq(status,pending_review)`) and pagination.
- [List targets](https://docs.adaptyvbio.com/api-reference/targets/list-targets.md): Lists validated antigens available for experiments. Each entry includes vendor and catalog identifiers, plus `pricing` where self-service pricing is available.
- [Submit custom target request](https://docs.adaptyvbio.com/api-reference/targets/submit-custom-target-request.md): Submit a new custom target (antigen) for staff review. At least one of `sequence` or `pdb_id` must be provided. The `product_id` must be unique within your organization.
- [Attenuate token](https://docs.adaptyvbio.com/api-reference/tokens/attenuate-token.md): Add restrictions to an existing token without needing the private key.
- [List tokens](https://docs.adaptyvbio.com/api-reference/tokens/list-tokens.md): Returns a flat, paginated list of all tokens (root and attenuated) the caller owns. Each item carries lineage fields (`parent_token_id`, `root_token_id`, `kind`) so callers can reconstruct the derivation tree. Admins with global scope see all tokens across all users.
- [Revoke the calling token and its entire lineage](https://docs.adaptyvbio.com/api-reference/tokens/revoke-the-calling-token-and-its-entire-lineage.md): Revokes the root token used to authenticate this request and all of its attenuated descendants, making the entire token family invalid for future API calls.
- [List updates](https://docs.adaptyvbio.com/api-reference/updates/list-updates.md): Returns the experiment update feed, newest first: status changes, progress markers, and completion events. Use `limit` and `offset` query parameters for pagination. Filter by experiment or type using the `filter` parameter, e.g. `filter=eq(experiment_id,<uuid>)` or `filter=in(experiment_id,uuid1,uui…
- [Changelog](https://docs.adaptyvbio.com/changelog/changelog.md): Track updates and changes to Adaptyv Bio's documentation and services
- [Binding Data Package](https://docs.adaptyvbio.com/docs/experiment-setup/binding-data-package.md): What arrives in your downloadable binding data bundle and how to work with it.
- [Creating Experiments](https://docs.adaptyvbio.com/docs/experiment-setup/creating-experiments.md): Learn how to create experiments
- [Supported Protein Formats](https://docs.adaptyvbio.com/docs/experiment-setup/supported-protein-formats.md): We supports a wide range of protein types
- [Target Proteins](https://docs.adaptyvbio.com/docs/experiment-setup/target-proteins.md): We can work with nearly any soluble protein target that is commercially available, or we can custom express proteins for you. Browse our target catalog for an overview of available targets. If you need a custom or proprietary target, we can help source and prepare the appropriate materials.
- [Binding](https://docs.adaptyvbio.com/docs/experiment-types/binding.md): Measure whether and how strongly your proteins bind their targets
- [Enzyme Activity](https://docs.adaptyvbio.com/docs/experiment-types/enzyme-activity.md): Quantify catalytic performance with simple, comparable readouts
- [Expression](https://docs.adaptyvbio.com/docs/experiment-types/expression.md): Test and quantify expression for your designed proteins.
- [Thermostability](https://docs.adaptyvbio.com/docs/experiment-types/thermostability.md): Measure thermal stability (Tm) to de-risk development and formulations
- [Introduction](https://docs.adaptyvbio.com/docs/getting-started/introduction.md): Adaptyv is a cloud lab that turns protein sequences into reliable experimental data—fast.
- [Project Workflow](https://docs.adaptyvbio.com/docs/getting-started/project-workflow.md): End-to-end workflow from configuration to data delivery
- [Improve Protein Expression](https://docs.adaptyvbio.com/guides/improve-protein-expression.md): Practical strategies to get your proteins expressing better on our platform
- [Coming Soon](https://docs.adaptyvbio.com/guides/protein-design-101/overview.md)
- [AlphaFold‑Multimer](https://docs.adaptyvbio.com/wiki/models/alphafold-multimer.md): Structure prediction for protein complexes with interface confidence metrics (e.g., ipTM)
- [ESM](https://docs.adaptyvbio.com/wiki/models/esm.md): Evolutionary Scale Modeling: protein LMs for representation, structure, and design
- [ipTM](https://docs.adaptyvbio.com/wiki/models/iptm.md): Interface predicted TM-score from AlphaFold‑Multimer for complex/interface quality
- [pSAE](https://docs.adaptyvbio.com/wiki/models/psae.md): Percent Solvent‑Accessible Exposed hydrophobicity (and related exposure metrics)
- [SolubleMPNN](https://docs.adaptyvbio.com/wiki/models/solublempnn.md): Sequence design with solubility-aware objectives
- [Fab](https://docs.adaptyvbio.com/wiki/proteins/fab.md): Antibody fragment containing one antigen-binding site
- [IgG](https://docs.adaptyvbio.com/wiki/proteins/igg.md): Full-length antibody format with two antigen-binding sites
- [Natural Ligands](https://docs.adaptyvbio.com/wiki/proteins/ligands.md): Endogenous peptides, proteins, or small molecules that bind biological targets
- [Miniproteins](https://docs.adaptyvbio.com/wiki/proteins/miniproteins.md): De novo or engineered small proteins with stable, designed folds
- [Peptides](https://docs.adaptyvbio.com/wiki/proteins/peptides.md): Short amino acid chains used as binders, modulators, and scaffolds
- [Protein Conjugates](https://docs.adaptyvbio.com/wiki/proteins/protein-conjugates.md): We provide binding targets expressed with various conjugates
- [Expression Systems](https://docs.adaptyvbio.com/wiki/proteins/protein-expression-systems.md): We provide binding targets expressed in various expression systems
- [scFv](https://docs.adaptyvbio.com/wiki/proteins/scfv.md): Minimal antibody fragment with variable domains linked by a peptide
- [VHH (Nanobodies)](https://docs.adaptyvbio.com/wiki/proteins/vhh.md): Single-domain antibody fragment derived from camelids
- [Biolayer Interferometry (BLI)](https://docs.adaptyvbio.com/wiki/technologies/BLI.md): Label-free optical technique for real-time protein binding measurements
- [Surface Plasmon Resonance (SPR)](https://docs.adaptyvbio.com/wiki/technologies/SPR.md): Label-free, real-time binding kinetics and affinity measurements
- [Affinity Tag Purification](https://docs.adaptyvbio.com/wiki/technologies/affinity-tag-purification.md): High-throughput protein purification using engineered affinity tags for rapid isolation and concentration
- [Capillary Electrophoresis (CE)](https://docs.adaptyvbio.com/wiki/technologies/capillary-electrophoresis.md): Capillary electrophoresis for quantitative analysis of protein expression, purity, and heterogeneity
- [Cell-Free Protein Expression](https://docs.adaptyvbio.com/wiki/technologies/cell-free-protein-expression.md): High-throughput protein production using cell-free expression systems for rapid prototyping and functional studies
- [HPLC-SEC](https://docs.adaptyvbio.com/wiki/technologies/hplc-sec.md): High-Performance Liquid Chromatography Size-Exclusion Chromatography for protein aggregation detection and quality control
- [nanoDSF](https://docs.adaptyvbio.com/wiki/technologies/nanodsf.md): Nano Differential Scanning Fluorimetry for protein thermostability assessment and melting temperature determination
- [Quant-iT Protein Assay (Qubit)](https://docs.adaptyvbio.com/wiki/technologies/quant-it.md): Fluorescent dye–based protein quantification for sensitive expression measurements
- [Split GFP Quantification](https://docs.adaptyvbio.com/wiki/technologies/split-GFP.md): Split GFP system for direct quantification of protein expression and qualitative yield estimation

## OpenAPI Specs

- [openapi](https://docs.adaptyvbio.com/api-reference/openapi.json)

## Optional

- [Careers](https://www.adaptyvbio.com/careers)
- [Blog](https://www.adaptyvbio.com/blog)
- [Experiment Configurator](https://start.adaptyvbio.com)
- [Foundry Portal](https://foundry.adaptyvbio.com)